Serological Detection of Human Parvovirus B19 Infection in various types of leukemia Using ELISA Among Iraqi Patients
Author(s):
Ruqayh Raad Mutter1, Ruaa Abdulazeez Mohammed1, Rusul Waleed Ali2, Ruaa Adnan Ali2, Raneen Ihsan Saleem3, Alaa saad hasan3
Date: 09/10/2026
doi: https://doi.org/10.5281/zenodo.8425890
Abstract
Background and Aim
The association of parvovirus B19 with various blood disorders is a major concern for many cancer
researchers. This study demonstrated the relationship between parvovirus B19 infection and different
types of leukemia in Iraqi patients.
Method
A cross-sectional study was conducted at a hospital, involving 80 individuals aged 16–70 years. They
underwent testing for parvovirus B19 using an ELISA assay. The study was based on inclusion and
exclusion criteria. Inclusion criteria included a confirmed diagnosis of leukemia and the provision of
voluntary informed consent. Exclusion criteria included co-infection with other known hematological or
viral diseases, pregnancy, serious underlying medical conditions, patients who had undergone
hematopoietic stem cell transplantation or other treatments, and patients who chose not to participate or
withdrew their consent. The study was conducted after obtaining ethical approval from the university's
ethics committee and according to the Helsinki declaration.
Results
Laboratory tests reveal high levels of importance for the data, with no correlation between pressure, heart
rate, and white blood cells. The rate of improvement, risk rate, and quality of life are also significant, with
the second group showing the best improvement at 32%. The highest risk rate was in the first group at
15%, followed by the third group at 14%, the second group at 10%, and the third group at 9%. The average
quality of life rate was highest in the second group at 38%. The data is statistically significant and can be
relied upon, indicating its importance in the treatment of leukemia.
Conclusion
Acute myeloid leukemia patients have moderate associations with B19 virus and antibodies, with B19
virus being more prevalent than other conditions.
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