Evaluating and comparing changes in lipid profile of women across age groups 22-65 years

Author(s): Alaa Adnan Aljanabi
Date: 09/10/2026
doi: https://doi.org/10.5281/zenodo.8425890

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Abstract

Background   
Disturbances in lipid profile parameters are significant indicators of cardiovascular disease. While age is 
a factor influencing lipid metabolism, the response of specific lipid profile components to this factor 
varies; consequently, the relationship between age and the lipid profile requires further study to elucidate 
the nature of this association. 
Objectives 
The study aimed to evaluate the levels of lipid profile components—specifically TC, TG    , HDL-C  and 
LDL-C  —across four progressive age groups  , and to determine the relationship between age and changes 
in the levels of these components. 
Methods 
This cross-sectional study was conducted at Imam Al-Hussein Medical City, involving blood samples 
from 92 apparently healthy women. The samples were divided into four age groups  ,Lipid profiles were 
measured using laboratory methods, and Statistical analysis was performed using appropriate tests at P < 
0.05. 
Results 
The study results indicated no significant differences in TC and LDL-C levels among the four age groups 
studied  ,however  significant differences were observed in TG and HDL-C levels. The )35–44 ( age group 
exhibited the highest TG levels and the lowest HDL-C levels compared to the other age groups. 
Conclusion 
The study results indicate a selective relationship between age and components of the lipid profile in 
women—specifically TG and HDL-C  as these were the most affected by age compared to TC and LDL
C. Consequently, these findings underscore the necessity of continuously monitoring the levels of these 
components, particularly during middle age, as a preventive measure to avoid metabolic disorders and the 
potential future diseases associated with them.

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